Final Results of NRG Oncology RTOG 0246: An Organ Preserving Selective Resection Strategy in Esophageal Cancer Patients Treated with Definitive Chemoradiation

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Besides the neutralization of free radicals produced in phase 1 liver metabolism of chemical toxins, GSH also participates in the protection from the resulting electrophilic substrates through the intervention of glutathione-S-transferases (GSTs)
Kassis ES, Vaporciyan AA, Swisher SG , Correa AM, Bekele BN, Erasmus JJ, Hofstetter WL, Komaki R, Mehran RJ, Moran CA, Pisters KM, Rice DC, Walsh GL, Roth JA
The gene responsible for type 2 Bartter encodes the renal outer medullary K + transporter identified as ROMK